High Triglycerides: Health Risks
Researchers have linked elevated levels of triglycerides to an increased risk of heart attack. In a Harvard-led study the scientists noted that high triglycerides alone increased the risk of heart attack nearly three-fold. And people with the highest ratio of triglycerides to HDL -- the "good" cholesterol -- had 16 times the risk of heart attack as those with the lowest ratio of triglycerides to HDL in the study of 340 heart attack patients and 340 of their healthy, same age counterparts.
The ratio of triglycerides to HDL was the strongest predictor of a heart attack, even more accurate than the LDL/HDL ratio." (Circulation 1997;96:2520-2525).
However, the association between triglycerides and HDL cholesterol is the most difficult to sort out. It turns out that whenever triglycerides are increased, HDL cholesterol decreases. So is the increased risk seen with high triglycerides due to the triglycerides themselves, or to the associated reduction in HDL cholesterol (the "good" cholesterol) and increase in LDL cholesterol (the "bad" cholesterol). So far, nobody can say for sure.
The problem is, people with elevated triglyceride levels almost invariably have other major risk factors for heart disease (mainly obesity, diabetes, and/or high blood pressure), and, so far, it has not been possible to sort out whether the triglycerides themselves pose an independent risk.
However, recent evidence strongly suggests that an elevated triglyceride level is a significant risk factor for cardiac disease.
The Helsinki Heart Study
The Helsinki Heart Study found that people with a high blood triglycerides level alone - that is that the participants had no other risk factors for heart disease - had about a 50 percent increased risk for coronary artery disease, compared to people with normal levels.
However, they had a 300 percent greater risk for coronary artery disease when they had both high blood triglyceride levels combined with high levels of LDL cholesterol.
Add borderline high blood pressure (140/90 mmHg or higher), and those people suffered a 500 percent increase!
Presence of excess triglycerides in the blood causes the viscosity (thickening) of blood and reduces the ability of arteries to enlarge. Each time, after high fat meals, your systemic arterial compliance (SAC) becomes decreased, what reflects primarily the stiffness of the aorta - the stiffer the aorta, the worse (Journal of the American College of Cardiology, June 1, 2000).
Triglycerides in higher amounts are significantly interrelated to the metabolism of HDL-"good" and LDL-"bad" cholesterol. They make the blood
- more "sluggish" and
- less capable of transporting oxygen to the tissues, particularly through the smallest blood vessels.
Therefore, elevated triglycerides are atherogenic – ie. more prone to becoming a part of artery-clogging atherosclerotic plaque leading to a heart attack or stroke.
The Need to Reduce "Desirable" Triglyceride Levels
Cardiologists at the University of Maryland Medical Center have developed more evidence that the “normal” or “desirable” levels of triglyceride may still pose a significant risk of heart disease.
The study provides a potential rationale for advocating much lower fasting triglyceride levels than those currently considered “desirable” (American Heart Association’s Scientific Sessions in Anaheim, California, November 13, 2001). Further, the study suggests less than 100 mg/dL is more appropriate, because once a meal is consumed, triglyceride levels rise.
Even when people have acceptable fasting triglyceride levels (the levels of triglyceride circulating in the blood after fasting overnight), after a high fat meal their triglyceride shoots up into levels that could put them at higher risk of heart disease.
However it is entirely possible that if people can lower their baseline triglyceride levels with diet changes and exercise, their heart disease risk may drop throughout the day, even after eating high fat meals.
In addition, the study evaluated the implications of “desirable” fasting triglyceride in 50 healthy, non-obese men and women with normal cholesterol levels, whose average age was 35.
After their fasting triglyceride was measured, each volunteer was given a milkshake, standardized at 70 grams of fat per square meter of body surface. Their triglycerides after a milk shake were measured at intervals of two, four, six, eight and ten hours.
For volunteers with a fasting triglyceride between 101 and 149, the triglyceride level at the peak, four hours after consuming the shake, averaged 200 mg/dL, putting them at dangerously high levels, despite the acceptable fasting levels.
However, in volunteers with a fasting triglyceride of less than 100, the four-hour peak triglyceride after the milkshake was only 124 mg/dL on average.
People with triglyceride levels at or above 100 were 50 percent more likely than those with lower levels to suffer from future heart attacks, need bypass surgery or angioplasty, or die from heart disease.
The average triglyceride level in the United States is 134 mg/dL and is considerably higher than triglyceride levels below 100 mg/dL commonly observed in countries where heart disease rates are low.
Higher triglyceride levels are associated with not only increase in body weight but also a disturbing increase in diabetes. It is a two-sided problem, because people with high triglycerides often develop insulin resistance, a major factor in the most common type of diabetes. In some cases, high triglycerides are identified years before the onset of diabetes.
Triglyceride is a fat that always circulates in the blood, especially after a meal high in saturated fat. Enzymes normally break down these fat particles, but when the process is not working efficiently, triglycerides that are only partially broken down can cause fatty deposits in blood vessels, leading to atherosclerosis, also known as narrowing of the arteries.
Triglycerides can also increase the risk of blood clots, which combine with fatty deposits in the coronary vessels to cause heart attacks.
The following video shows series of graphic visual representations caused by poor dietary choices. It is a perfect exemplification of the old adage, "A (motion) picture is worth a thousand words."
Increased Risk of Ischemic Stroke
Researchers have linked high levels of triglycerides to an increased risk of stroke. High triglycerides and the low levels of HDL, or "good" cholesterol that usually coexist, are important risk factors for the main type of stroke, called ischemic stroke, among people with heart disease.
In the December 11, 2001, edition of the medical journal Circulation, it was noted that ischemic strokes, or brain attacks, which occur when a clot or narrowed artery cuts off the brain’s blood supply, account for about 80 per cent of all strokes. The other 20 per cent are due to broken blood vessels in the brain.
Further, it was noted that people with more than 200 mg of triglycerides per dL of blood were nearly 30 per cent more likely to have an ischemic stroke, or TIA, than people with lower levels of the blood fats.
It is no surprise to read this. Thus a person who has an elevated level of triglycerides, which affects blood vessels in the brain, would have an increased risk of stroke. However, there is much more to this issue/problem.
Increased Risk of Fatty Liver and Pancreatitis
Blood triglycerides higher than 500 mg/dL put you at high risk for such problems as
- fatty liver and
- acute pancreatitis, leading to pancreatic injury.
In pancreatitis (inflammation of pancreas), pancreatic enzymes begin to digest the pancreas itself. This condition may lead to
- kidney failure,
- ARDS (acute respiratory distress syndrome),
- coma, or
- multisystem organ failure.
Furthermore, if you have elevated serum triglycerides it may indicate that
- you have some problem with insulin, either a pre-diabetic state, or frank diabetes; or
- you drink excessive amounts of alcohol and
- your liver isn't functioning properly.
If you have coronary heart disease, diabetes mellitus (type 2, or non-insulin-dependent diabetes), or multiple risk factors, your triglyceride goal should be less than 100 mg/dL (but not lower than 70 mg/dL).
When triglyceride levels are greater than 150mg/dL, LDL-"bad" cholesterol is almost always a small, dense particle that is highly oxidizable and very atherogenic - producing degenerative changes in arterial walls, especially in those with glucose intolerance or diabetes mellitus (type 2 diabetes).
TGs Formula® II: Advanced Blood Lipid Support
Hello, I'm Andrew Mierzejewski, a master formulator, registered holistic nutritionist and biohealing practitioner with over 20 years of experience. I personally guarantee the quality, efficacy and safety of the supplements recommended here. And I am sure that when taken properly and wisely they can be of great benefit to your health or the health of someone you love or hold dear.
From time to time, you may hear or read scientific reports allegedly showing that such-and-such herb or vitamin doesn't work or may even be harmful to your health.
They are a perfect example of the existing and often uninformed prejudice against nutritional supplements.
We sincerely hope that you do not believe in such anti-supplement nonsense discouraging their use.
TGs Formula II is our new, streamlined and reformulated TGs Formula®, hence its name: TGs Formula II - a specialty naturopathic formulation designed to optimize the metabolism of lipids (fats) in the body ("TGs" stands for "triglycerides").
Therefore, like its predecessor TGs Formula II demonstrates the ability to help:
- reduce the levels of blood triglycerides,
- increase the levels of HDL-"good" cholesterol,
- reduce the levels of LDL-"bad" cholesterol,
- reduce the levels of Lp(a), a killer component of LDL-cholesterol
- correct and optimize the natural processes (biochemical and enzymatic) of fat metabolism,
- stimulate plasma lipoprotein lipase (involved in the catabolism of triglycerides),
- protect the liver against increases in fatty acids, and
- improve the ratio of unsaturated fatty acids to saturated fatty acids in the blood.
TGs Formula II not only keeps the blood fats in check (as drugs do), but actually helps your body rebuild the organs and systems that control your blood lipids - without side effects. Unlike pharmaceutical drugs, it is very body-friendly.
TGs Formula II: Mechanism of Action
It should be pointed out that along with lowering high blood triglyceride levels, TGs Formula II also helps to reduce elevated levels of Lipoprotein(a) and LDL-"bad" cholesterol. It is also effective in helping to raise the levels of HDL-"good" cholesterol.
All nutrients in TGs Formula II:
- work by supporting biochemical and enzymatic processes,
- work best in combination with each other (nutrition is like a chain - all of the links have to be strong in order to obtain meaningful results),
- have an effect only if they are absent in the body (a given supplement will likely have no effect unless the person taking it already has a deficiency in that particular factor),
- work gradually and gently over a period of time,
- deal with causes (if a given condition is caused by the lack of specific nutrients, then adding them to the diet will tend to correct the problem, to the extent that any damage done is not irreversible),
- do not require monitoring as closely as do drugs (consequences of nutritional excesses are minimal - there is a wide margin of safety!),
- slow down the degenerative processes in the body caused by deficiency diseases, such as atherosclerosis.
It is important to remember that all ingredients in TGs Formula II are:
- both natural and essential to the body, therefore
- safe (there has never been a single documented fatality caused by taking dietary supplements),
- required by those who need larger amounts of nutritional factors, because of their longer standing deficiencies and/or poor assimilation of nutrients,
- best taken with meals (they are more efficiently absorbed with food and they enhance the assimilation of other food factors).
TGs Formula II: You Will Benefit*
As a dietary supplement to optimize the blood lipid levels, TGs Formula II is recommended for:
- bringing elevated blood triglycerides down to healthy level,
- keeping levels of HDL-"good" cholesterol within healthy range,
- encouraging healthy blood viscosity (the thickness and stickiness of blood - a critical determinant of friction against the vessel walls),
- improving blood flow,
- supporting proper cardiovascular function.
All nutrients are present in specific ratios and amounts in order to correct longer standing imbalances that are known to contribute to elevated blood fat levels..
TGs Formula II
Naturopathic Blood Lipid Support
Dietary Supplement: 90 Vegetarian Capsules
SUPPLEMENT FACTS: Amount Per Serving (3 Capsules)
|Chromium (as Chromium Polynicotinate)
|Red Yeast Rice
|Policosanols (from Sugar Cane)
|Total Phytosterols (from Soy):
| Beta sitosterol
|Guggul Lipids Powder
|Artichoke (Leaf) Extract
|Other Ingredients: Rice Flour, Vegetable Cellulose, Vegetarian Leucine.
|This product is manufactured in a NSF GMP registered facility in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.
||QUALITY & SAFETY
|Suggested Use: As a dietary supplement, take 3 capsules daily with food.
Daily amount can be divided between AM and PM, or as directed by your healthcare practitioner.
|CAUTION: If you are pregnant, nursing or taking any cholesterol-lowering medication, consult your healthcare practitioner before using this product.
|FULL OF HEALTH, INC. Since 1996
TGs Formula® II : A Dietary Supplement to Support Cardiovascular Function and the Maintenance of Lipids within Normal Range *
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Full of Health and TGs Formula are registered trademarks of Full of Health, Inc.
TGs Formula II: Recommended Intake
Although there is still no consensus regarding the value necessitating initiation of triglyceride drug treatment, according to most physicians, at the triglyceride level:
- over 200 mg/dL (2.3 mmol/L) begins the need for implementation of proper dietary, eating habits, and
- over 300 mg/dL (3.4 mmol/L) a pharmacological (drug) treatment should be started.
According to some experts, however, blood triglycerides:
- in women with levels above 190 mg/dL (2.2 mmol/L) are the most significant predictor of heart disease;
- in males, the danger level starts over 400 mg/dL (4.6 mmol/L).
On the other hand, the triglyceride goal of 70 mg/dL - 100 mg/dL (0.8 mmol/L - 1.1 mmol/L) should be for those who have:
- coronary heart disease,
- diabetes mellitus (type 2 or non-insulin-dependent diabetes), or
- multiple risk factors (elevated blood lipids, high diastolic/minimum blood pressure and cigarette smoking).
It has been documented that by more aggressively treating elevated blood triglycerides, the risk of ischemic heart disease (IHD) can be significantly reduced.
Therefore, if you are not, and rightly so, a proponent of the pharmacological (drug) treatment - often prompting multiple side effects - you can choose the nutritional way of bringing high blood triglycerides down to healthy levels. As opposed to prescription drugs, taking TGs Formula II is something you can do on your own - and get results.
The following recommendations will help you determine your needs based on your actual blood test results:
I. How to Bring Your Triglycerides Down
Option #1: Borderline High Triglycerides
If your triglycerides level is between 150 mg/dL and 199 mg/dL, or 1.7 mmol/L - 2.3 mmol/L ("borderline high") - for best results, you should be on TGs Formula II for at least 2 consecutive months, taking one (1) capsule three times daily with substantial meals.
Therefore, you would need at least one (2) bottles of TGs Formula II to improve your next blood test results for triglycerides.
Option #2: High Triglycerides
If your triglycerides level is between 200 mg/dL and 500 mg/dL, or 2.3 mmol/L – 5.6 mmol/L ("high") - for best results, you should be on TGs Formula II for at least 2 consecutive months, taking two (2) capsules three times daily with substantial meals.
Therefore, you would need four (4) bottles of TGs Formula II to improve your next blood test results for triglycerides.
Option #3: Very High Triglycerides
If your triglycerides level is higher than 500 mg/dL, or >5.6 mmol/L ("very high") - for best results, you should be on TGs Formula II for at least 2 consecutive months, taking three (3) capsules three times daily with substantial meals.
Therefore, you would need six (6) bottles of TGs Formula II to improve your next blood test results for triglycerides.
REMEMBER: It has been shown that atherogenic (atheromas-forming) hypertriglyceridemia starts at the triglyceride level of 150 mg/dL (1.7 mmol/L) initiating degenerative changes in the cardiovascular system. Therefore, for people with levels greater than 150 milligrams per deciliter range, therapeutic lifestyle changes are necessary, such as exercising, losing weight, swapping unhealthy fats for healthy ones, and the like.
- If you are a diabetic, or have a history of a heart attack or stroke, for full benefits, in addition to TGs Formula II you should consider taking a quality supplemental EPA, such as UltraPure Mega EPA.
- If you want to be certain that your gut gets TGs Formula II (and any other supplements you've been taking!) into the bloodstream where it can do its work effectively in bringing your high blood triglycerides down to healthy levels, you should consider taking quality supplemental digestive enzymes, such as XTRAGEST.
II. How to Maintain Your Triglycerides Within Normal Range
Unfortunately, after bringing triglycerides down to a desired level, it is not always easy, or even possible, to maintain them within normal range through the dietary and lifestyle changes alone.
This is where TGs Formula II comes in handy.
Its daily recommended maintenance dose can be deteremined as follows:
- If your best achieved level was under 150 mg/dL, or 1.7 mmol/L), you would need to take only one (1) capsule of TGs Formula II daily.
- If your best achieved level was slightly over 150 mg/dL, or 1.7 mmol/L, you would need to take two (2) capsules of TGs Formula II daily.
- If your best achieved level was slightly under 200 mg/dL, or 2.3 mmol/L, you would need to take three (3) capsules of TGs Formula II daily.
After three (3) consecutive months, you should do a fasting blood test to see the efficacy of this approach.
If your results were satisfactory, you may
- continue the above protocol or discontinue taking TGs Formula II (and relying on the dietary/lifestyle changes alone) for three (3) consecutive months and then repeat the blood test to see how your body responds.
If your results were unsatisfactory, you should
- review your dietary and lifestyle changes and go back for another three (3) consecutive months to the therapeutic intake of TGs Formula II based on the actual level of your blood triglycerides, and then repeat the blood test to see how your body responds.
PLEASE NOTE: If you are a diabetic, or have a history of a heart attack or stroke, for full benefits, in addition to TGs Formula II you should consider taking a quality supplemental EPA, such as UltraPure Mega EPA.
The Take-Home Message:
If you really want to maintain your triglycererides within normal range, please follow the above recommendations to the letter.
III. How to Test Properly Your Blood for Triglycerides
Although not necessary for measuring cholesterol, the test for triglycerides should always be done when you are fasting.
Therefore, for 12 to 14 hours before the blood sample is drawn, only water is permitted. In other words, nothing except water is permitted from bedtime until you get your blood work done next morning when a lab opens (it's good to have two cups of water (473 mL) one hour before the collection of blood).
In addition, consumption of alcohol and any vitamin supplements is not permitted for the 24 hours just before the fasting blood work.
If you are currently on antihistamines, antibiotics or cortisone treatment only, you need to call the lab or your doctor for more information on how to proceed.
Why is that?
Anything taken in, other than water during that time, morning coffee or juice, for example, can elevate the triglycerides levels as they change dramatically in response to meals, increasing as much as 5 to 10 times higher than fasting levels just a few hours after eating.
Therefore, when scheduling your triglyceride test you need take your weekend activities into account. Because after a weekend of beer and pizza, or desserts, cakes or ice-cream, your Monday blood work readings can be much higher than on the other days.
Unfortunately, your doctor, even the "highly regarded" one, may have you take a triglyceride blood test without informing you of all factors that might affect the results. You never know when he might be rushed or inexperienced, or simply overly comfortable with a procedure, then end up taking a shortcut at your expense, recommending a drug or an uncomfortable, invasive procedure based solely on a suspect or false test result.
The Take-Home Lesson:
Always ask your doctor for specifics regarding factors that can create false positive or false negative blood test results.
TGs Formula II: Description of Nutrients*
I. HDL-"good" Cholesterol to LDL-"Bad" Cholesterol Ratio Support
- Red Yeast Rice (Monascus porporeus) is an all-natural whole food made from dried fermented rice. Red Rice Yeast naturally helps maintain triglyceride levels within normal ranges and contains unsaturated fatty acids that support the maintenance of serum lipids within normal ranges.
- Chromium is a trace mineral used by the body to regulate HDL-"good" cholesterol- to-LDL-"bad" cholesterol ratios. The Chromium Polynicotinate form ensures maximum bioavailability. The average American diet is chromium deficient.
- Phytosterols are plant steroid alcohols that have been shown to support the maintenance of triglycerides within normal range by blocking the over-absorption of triglycerides. TGs Formula II contains a phytosterol complex from soy that yields 90% phytosterols including 180 mg of Beta-sitosterol.
II. Lipids Synthesis and Circulation
- Policosanol is a complex that has been studied for its ability to reduce triglycerides synthesis by the liver, protect against peroxidation of lipids, aid healthy blood flow and support the maintenance of beneficial HDL cholesterol and triglycerides within normal range.
- Artichoke (Cynara scolymnus) Leaf Extract is a phytonutrient that has been shown to support triglycerides within normal ranges. Cynarin, a compound contained in artichokes, supports the production of bile, which may help the body to excrete cholesterol. Artichoke Leaf Extract helps balance activity of the enzyme responsible for maintaining triglyceride levels within normal ranges.
III. Antioxidant and Blood Viscosity Support
- Guggul lipids contain compounds known as guggul sterones. As antioxidants, they protect against lipid peroxidation.
- Coenzyme Q10 is critical in the generation of cellular energy. Coenzyme Q10 is an antioxidant found in the highest concentrations in the heart, liver, kidneys, spleen and pancreas.
- TGs Formula® II is a great addition to any diet and exercise program that is designed to support the maintenance of HDL-"good" cholestereol and triglycerides within normal healthy ranges.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
TGs Formula II: No Conlict with Prescription Drugs
A concern raised by some clients might be the possibility of conflict between prescription drugs and TGs Formula II. The good news is that there is no conflict. In fact, they can be taken at the same time.
The even better news is that, if you take prescription drugs along with TGs Formula II, you need to be monitored regularly by your physician, as you may need to reduce the amount of the drugs you are taking.
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TGs Formula II: Our Clients Write to Us
I do not expect you to judge the efficacy of TGs Formula II only on anecdotal reports. First, it is very difficult to verify the accuracy of these accounts. Second, you cannot generalize one person's experience to others.
I do believe, however, that all information is valuable when placed in a proper perspective. Although not a substitute for "valid science," personal experiences should be taken into consideration, especially as a means of communicating how some people get well.
February 23rd, 2016
Your TGs Formula works! I had my triglycerides over 400 and now they are less than 150.
I stopped using this Formula for some time and my triglycerides were very high again.
My doctor told me I have to take TGs Formula for the rest of my life, because I am allergic to medications for reducing blood triglycerides. This is my only alternative.
Thank you very much!
Edna V. S.
*The testimonial above has been presented as a true story. However, it has not been reviewed by Full of Health and is the opinion of the listed individual.
I thought you would want to know about my latest blood test after taking TGs Formula II and UltraPure Mega EPA:
I. On 5-21-2014:
Cholesterol - 279
Triglycerides - 624
Chol/HDL ratio - 9.0 (it should be 4.5 or less).
II. On 6-24-2014:
Cholesterol - 191
Triglycerides - 236
Chol/HDL ratio - 5.5 (it should be 4.5 or less).
Needless to say, I am very happy! You certainly made my day. I took your previous TGs Formula a few years ago. It worked too, but I developed a phobia about swallowing those big pills...
Thank you Full of Health/Andrew!
Cindy Van L.
*The testimonial above has been presented as a true story. However, it has not been reviewed by Full of Health and is the opinion of the listed individual.
Who says that specialty nutritional supplements do not work? Those, who think that micronutrients are not necessary for our health and that optimum nutrition is not important.
Why do they think and act that way?
Because they don't want to learn and just keep ignoring the impressive results - not only heard about, but also seen and experienced by people who have taken specialty nutritional supplements.
Important Question: How Is Your Digestion?
Take a moment to think about your digestion and ask yourself: "Do I experience any of the symptoms of indigestion?"
If your answer is "Yes" or "Not sure," then consider taking TGs Formula II along with XTRAGEST - or other broad-spectrum quality digestive aid - to ensure that you will fully benefit from it.
Only by optimizing your digestion you can be certain that your gut breaks down the TGs Formula II and gets it into the bloodstream where it can do its work effectively.
For more information, please call: 1. 705. 304. 6246 (US/Can)
Monday, Wednesday, Friday: 11:00 am - 3:00 pm EST (Holidays Excluded)
If there is nobody available to take your call, please .
We will get back to you next business day.
©2004-2017 TGs Formula.com: Bring High Triglycerides Down Naturally. Maintain Blood Lipids Within Normal Range & Healthy Levels. A Non-Pharmacological Approach to Hypertriglyceridemia. All Rights Reserved. The information on lowering elevated blood triglycerides and TGs Formula II provided herein is not intended to replace the medical advice. Consult a physician for an advice about any specific condition that may be related to high triglycerides.